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\u90bb\u82ef\u4e8c\u7532\u9178\u9150(PA)\u3001\u516d\u6c22\u90bb\u82ef\u4e8c\u7532\u9178\u9150(HHPA)\u3001\u7532\u57fa\u516d\u6c22\u90bb\u82ef\u4e8c\u7532\u9178\u9150(MHHPA)\u3001\u7532\u57fa\u56db\u6c22\u90bb\u82ef\u4e8c\u7532\u9178\u9150(MTHPA)\u7b49\u3002<\/p>\n<p><strong>\u56db\u3001\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\uff1a\u73af\u6c27\u6811\u8102\u7684\u201c\u5b88\u62a4\u5929\u4f7f\u201d<\/strong><\/p>\n<p><img decoding=\"async\" src=\"\/images\/74.jpg\" alt=\"\u73af\u6c27\u9178\u9150\u4f53\u7cfb\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\uff0c\u6709\u6548\u63d0\u5347\u73af\u6c27\u6811\u8102\u7684\u6574\u4f53\u8010\u8001\u5316\u6027\u80fd\"><\/p>\n<p><strong>\u56db\u3001\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\uff1a\u73af\u6c27\u6811\u8102\u7684\u201c\u5b88\u62a4\u5929\u4f7f\u201d<\/strong><\/p>\n<p>\u867d\u7136\u9178\u9150\u56fa\u5316\u4f53\u7cfb\u672c\u8eab\u5177\u6709\u4e00\u5b9a\u7684\u8010\u9ec4\u53d8\u6027\u80fd\uff0c\u4f46\u5728\u4e00\u4e9b\u5bf9\u8010\u9ec4\u53d8\u8981\u6c42\u66f4\u9ad8\u7684\u5e94\u7528\u573a\u5408\uff0c\u4ecd\u7136\u9700\u8981\u6dfb\u52a0\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u6765\u8fdb\u4e00\u6b65\u63d0\u9ad8\u5176\u6297\u8001\u5316\u80fd\u529b\u3002<\/p>\n<p>\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u5c31\u50cf\u4e00\u4f4d\u201c\u5b88\u62a4\u5929\u4f7f\u201d\uff0c\u901a\u8fc7\u5404\u79cd\u65b9\u5f0f\u6765\u4fdd\u62a4\u73af\u6c27\u6811\u8102\u514d\u53d7\u5149\u3001\u70ed\u3001\u6c27\u7b49\u56e0\u7d20\u7684\u4fb5\u8680\uff0c\u4ece\u800c\u5ef6\u7f13\u9ec4\u53d8\u7684\u53d1\u751f\u3002<\/p>\n<p>\u5e38\u89c1\u7684\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u4e3b\u8981\u6709\u4ee5\u4e0b\u51e0\u7c7b\uff1a<\/p>\n<ul>\n<li><strong>\u7d2b\u5916\u7ebf\u5438\u6536\u5242\uff08UVAs\uff09\uff1a<\/strong> \u5c31\u50cf\u4e00\u628a\u201c\u906e\u9633\u4f1e\u201d\uff0c\u80fd\u591f\u5438\u6536\u7d2b\u5916\u7ebf\uff0c\u5c06\u5176\u8f6c\u5316\u4e3a\u70ed\u80fd\u91ca\u653e\uff0c\u4ece\u800c\u51cf\u5c11\u7d2b\u5916\u7ebf\u5bf9\u73af\u6c27\u6811\u8102\u7684\u635f\u5bb3\u3002\u5e38\u89c1\u7684\u7d2b\u5916\u7ebf\u5438\u6536\u5242\u6709\u82ef\u5e76\u4e09\u5511\u7c7b\u3001\u4e8c\u82ef\u7532\u916e\u7c7b\u7b49\u3002<\/li>\n<li><strong>\u53d7\u963b\u80fa\u5149\u7a33\u5b9a\u5242\uff08HALS\uff09\uff1a<\/strong> \u5c31\u50cf\u4e00\u4f4d\u201c\u81ea\u7531\u57fa\u6e05\u9053\u592b\u201d\uff0c\u80fd\u591f\u6355\u83b7\u73af\u6c27\u6811\u8102\u5728\u5149\u6c27\u5316\u8fc7\u7a0b\u4e2d\u4ea7\u751f\u7684\u81ea\u7531\u57fa\uff0c\u963b\u6b62\u8fde\u9501\u53cd\u5e94\u7684\u53d1\u751f\u3002\u5e38\u89c1\u7684\u53d7\u963b\u80fa\u5149\u7a33\u5b9a\u5242\u6709\u884d\u751f\u7269\u7b49\u3002<\/li>\n<li><strong>\u6297\u6c27\u5242\uff1a<\/strong> \u5c31\u50cf\u4e00\u4f4d\u201c\u62a4\u536b\u6218\u58eb\u201d\uff0c\u80fd\u591f\u6291\u5236\u73af\u6c27\u6811\u8102\u7684\u70ed\u6c27\u5316\u8fc7\u7a0b\uff0c\u5ef6\u7f13\u9ec4\u53d8\u7684\u53d1\u751f\u3002\u5e38\u89c1\u7684\u6297\u6c27\u5242\u6709\u53d7\u963b\u915a\u7c7b\u3001\u4e9a\u78f7\u9178\u916f\u7c7b\u7b49\u3002<\/li>\n<li><strong> quenchers (\u731d\u706d\u5242) \uff1a<\/strong> \u901a\u8fc7\u80fd\u91cf\u8f6c\u79fb\u8fc7\u7a0b\u731d\u706d\u6fc0\u53d1\u6001\u5206\u5b50\uff0c\u4f7f\u5176\u56de\u5230\u57fa\u6001\uff0c\u4ece\u800c\u964d\u4f4e\u5149\u5316\u5b66\u53cd\u5e94\u7684\u6548\u7387\uff0c\u8fbe\u5230\u8010\u9ec4\u53d8\u7684\u6548\u679c\u3002<\/li>\n<li><strong>\u7279\u6b8a\u586b\u6599\uff1a<\/strong> \u67d0\u4e9b\u7eb3\u7c73\u586b\u6599\uff0c\u5982\u7eb3\u7c73\u4e8c\u6c27\u5316\u949b\u3001\u7eb3\u7c73\u6c27\u5316\u950c\u7b49\uff0c\u4e5f\u5177\u6709\u4e00\u5b9a\u7684\u7d2b\u5916\u7ebf\u5c4f\u853d\u4f5c\u7528\uff0c\u80fd\u591f\u63d0\u9ad8\u73af\u6c27\u6811\u8102\u7684\u8010\u9ec4\u53d8\u6027\u80fd\u3002<\/li>\n<\/ul>\n<p><strong>\u4e94\u3001\u73af\u6c27\u9178\u9150\u4f53\u7cfb\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\uff1a\u5f3a\u5f3a\u8054\u5408\uff0c\u6548\u679c\u52a0\u500d<\/strong><\/p>\n<p>\u73af\u6c27\u9178\u9150\u4f53\u7cfb\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\uff0c\u987e\u540d\u601d\u4e49\uff0c\u5c31\u662f\u4e13\u95e8\u4e3a\u73af\u6c27\u9178\u9150\u4f53\u7cfb\u8bbe\u8ba1\u7684\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u3002\u5b83\u901a\u5e38\u662f\u591a\u79cd\u8010\u9ec4\u53d8\u7ec4\u5206\u7684\u590d\u914d\u7269\uff0c\u80fd\u591f\u534f\u540c\u4f5c\u7528\uff0c\u53d1\u6325\u66f4\u4f73\u7684\u8010\u9ec4\u53d8\u6548\u679c\u3002<\/p>\n<p>\u73af\u6c27\u9178\u9150\u4f53\u7cfb\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u7684\u4f5c\u7528\u673a\u7406\u4e3b\u8981\u5305\u62ec\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/p>\n<ul>\n<li><strong>\u591a\u91cd\u9632\u62a4\uff1a<\/strong> \u7d2b\u5916\u7ebf\u5438\u6536\u5242\u3001\u53d7\u963b\u80fa\u5149\u7a33\u5b9a\u5242\u3001\u6297\u6c27\u5242\u7b49\u591a\u91cd\u9632\u62a4\u673a\u5236\uff0c\u5168\u65b9\u4f4d\u4fdd\u62a4\u73af\u6c27\u6811\u8102\u514d\u53d7\u5149\u3001\u70ed\u3001\u6c27\u7b49\u56e0\u7d20\u7684\u4fb5\u8680\u3002<\/li>\n<li><strong>\u534f\u540c\u589e\u6548\uff1a<\/strong> \u4e0d\u540c\u7ec4\u5206\u4e4b\u95f4\u4ea7\u751f\u534f\u540c\u6548\u5e94\uff0c\u4f8b\u5982\uff0c\u7d2b\u5916\u7ebf\u5438\u6536\u5242\u5438\u6536\u7d2b\u5916\u7ebf\u540e\uff0c\u53ef\u80fd\u4f1a\u4ea7\u751f\u4e00\u4e9b\u81ea\u7531\u57fa\uff0c\u800c\u53d7\u963b\u80fa\u5149\u7a33\u5b9a\u5242\u53ef\u4ee5\u53ca\u65f6\u6e05\u9664\u8fd9\u4e9b\u81ea\u7531\u57fa\uff0c\u4ece\u800c\u63d0\u9ad8\u6574\u4f53\u7684\u8010\u9ec4\u53d8\u6548\u679c\u3002<\/li>\n<li><strong>\u76f8\u5bb9\u6027\u597d\uff1a<\/strong> \u4e13\u95e8\u4e3a\u73af\u6c27\u9178\u9150\u4f53\u7cfb\u8bbe\u8ba1\uff0c\u4e0e\u73af\u6c27\u6811\u8102\u3001\u9178\u9150\u56fa\u5316\u5242\u7b49\u5177\u6709\u826f\u597d\u7684\u76f8\u5bb9\u6027\uff0c\u4e0d\u4f1a\u5f71\u54cd\u56fa\u5316\u8fc7\u7a0b\u548c\u56fa\u5316\u7269\u7684\u6027\u80fd\u3002<\/li>\n<\/ul>\n<table>\n<thead>\n<tr>\n<th style=\"text-align: left\">\u4ea7\u54c1\u540d\u79f0<\/th>\n<th style=\"text-align: left\">\u4e3b\u8981\u6210\u5206<\/th>\n<th style=\"text-align: left\">\u5916\u89c2<\/th>\n<th style=\"text-align: left\">\u63a8\u8350\u7528\u91cf (%)<\/th>\n<th style=\"text-align: left\">\u9002\u7528\u4f53\u7cfb<\/th>\n<th style=\"text-align: left\">\u7279\u70b9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"text-align: left\">A\u578b\u8010\u9ec4\u53d8\u5242<\/td>\n<td style=\"text-align: left\">\u7d2b\u5916\u7ebf\u5438\u6536\u5242 + HALS + \u6297\u6c27\u5242<\/td>\n<td style=\"text-align: left\">\u900f\u660e\u6db2\u4f53<\/td>\n<td style=\"text-align: left\">0.5-2.0<\/td>\n<td style=\"text-align: left\">\u73af\u6c27\u9178\u9150\u4f53\u7cfb<\/td>\n<td style=\"text-align: left\">\u5e7f\u8c31\u9632\u62a4\uff0c\u8010\u5019\u6027\u4f18\u5f02\uff0c\u76f8\u5bb9\u6027\u597d<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: left\">B\u578b\u8010\u9ec4\u53d8\u5242<\/td>\n<td style=\"text-align: left\">\u7eb3\u7c73\u4e8c\u6c27\u5316\u949b + HALS<\/td>\n<td style=\"text-align: left\">\u767d\u8272\u7c89\u672b<\/td>\n<td style=\"text-align: left\">0.2-1.0<\/td>\n<td style=\"text-align: left\">\u73af\u6c27\u9178\u9150\u4f53\u7cfb<\/td>\n<td style=\"text-align: left\">\u7d2b\u5916\u7ebf\u5c4f\u853d\uff0c\u63d0\u9ad8\u8868\u9762\u786c\u5ea6\uff0c\u5206\u6563\u6027\u597d<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: left\">C\u578b\u8010\u9ec4\u53d8\u5242<\/td>\n<td style=\"text-align: left\">\u82ef\u5e76\u4e09\u5511\u7c7b + \u53d7\u963b\u915a\u7c7b\u6297\u6c27\u5242<\/td>\n<td style=\"text-align: left\">\u6de1\u9ec4\u8272\u6db2\u4f53<\/td>\n<td style=\"text-align: left\">1.0-3.0<\/td>\n<td style=\"text-align: left\">\u73af\u6c27\u9178\u9150\u4f53\u7cfb<\/td>\n<td style=\"text-align: left\">\u6210\u672c\u8f83\u4f4e\uff0c\u9632\u62a4\u6548\u679c\u8f83\u597d\uff0c\u9002\u7528\u4e8e\u5bf9\u6210\u672c\u654f\u611f\u7684\u5e94\u7528<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: left\">D\u578b\u8010\u9ec4\u53d8\u5242<\/td>\n<td style=\"text-align: left\">Quencher<\/td>\n<td style=\"text-align: left\">\u900f\u660e\u6db2\u4f53<\/td>\n<td style=\"text-align: left\">0.1-0.5<\/td>\n<td style=\"text-align: left\">\u73af\u6c27\u9178\u9150\u4f53\u7cfb\/\u4e19\u70ef\u9178\u4f53\u7cfb<\/td>\n<td style=\"text-align: left\">\u663e\u8457\u6539\u5584\u6750\u6599\u7684\u8010\u9ec4\u53d8\u6027\uff0c\u5c24\u5176\u5bf9\u5149\u7167\u5f15\u8d77\u7684\u9ec4\u53d8\u6709\u7279\u6548\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>\u516d\u3001\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u7684\u5e94\u7528\u6280\u5de7\uff1a\u8ba9\u73af\u6c27\u6811\u8102\u201c\u9752\u6625\u7115\u53d1\u201d<\/strong><\/p>\n<p>\u4e3a\u4e86\u5145\u5206\u53d1\u6325\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u7684\u6548\u7528\uff0c\u5728\u4f7f\u7528\u8fc7\u7a0b\u4e2d\u8fd8\u9700\u8981\u6ce8\u610f\u4ee5\u4e0b\u51e0\u70b9\uff1a<\/p>\n<ul>\n<li><strong>\u9009\u62e9\u5408\u9002\u7684\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\uff1a<\/strong> \u4e0d\u540c\u7684\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u5177\u6709\u4e0d\u540c\u7684\u7279\u70b9\u548c\u9002\u7528\u8303\u56f4\uff0c\u5e94\u6839\u636e\u5177\u4f53\u7684\u5e94\u7528\u9700\u6c42\u548c\u4f53\u7cfb\u7279\u70b9\u9009\u62e9\u5408\u9002\u7684\u7c7b\u578b\u3002<\/li>\n<li><strong>\u63a7\u5236\u7528\u91cf\uff1a<\/strong> \u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u7684\u7528\u91cf\u5e76\u975e\u8d8a\u591a\u8d8a\u597d\uff0c\u8fc7\u91cf\u6dfb\u52a0\u53ef\u80fd\u4f1a\u5f71\u54cd\u56fa\u5316\u7269\u7684\u6027\u80fd\uff0c\u751a\u81f3\u4ea7\u751f\u8d1f\u9762\u5f71\u54cd\u3002\u4e00\u822c\u6765\u8bf4\uff0c\u5e94\u6839\u636e\u4ea7\u54c1\u8bf4\u660e\u4e66\u6216\u5b9e\u9a8c\u7ed3\u679c\u786e\u5b9a\u4f73\u7528\u91cf\u3002<\/li>\n<li><strong>\u5145\u5206\u5206\u6563\uff1a<\/strong> \u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u5e94\u5145\u5206\u5206\u6563\u5728\u73af\u6c27\u6811\u8102\u4f53\u7cfb\u4e2d\uff0c\u4ee5\u786e\u4fdd\u5176\u80fd\u591f\u5747\u5300\u5730\u53d1\u6325\u4f5c\u7528\u3002\u5bf9\u4e8e\u56fa\u4f53\u7c89\u672b\u72b6\u7684\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\uff0c\u5efa\u8bae\u5148\u8fdb\u884c\u9884\u5206\u6563\u5904\u7406\uff0c\u4f8b\u5982\uff0c\u4f7f\u7528\u5c11\u91cf\u6eb6\u5242\u5c06\u5176\u6eb6\u89e3\u6216\u5206\u6563\u6210\u6d46\u6599\u3002<\/li>\n<li><strong>\u907f\u514d\u9ad8\u6e29\uff1a<\/strong> \u5728\u6dfb\u52a0\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u7684\u8fc7\u7a0b\u4e2d\uff0c\u5e94\u907f\u514d\u9ad8\u6e29\u64cd\u4f5c\uff0c\u4ee5\u9632\u6b62\u5176\u5206\u89e3\u6216\u5931\u6548\u3002<\/li>\n<li><strong>\u6ce8\u610f\u76f8\u5bb9\u6027\uff1a<\/strong> \u5728\u9009\u62e9\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u65f6\uff0c\u5e94\u6ce8\u610f\u5176\u4e0e\u73af\u6c27\u6811\u8102\u3001\u9178\u9150\u56fa\u5316\u5242\u7b49\u7ec4\u5206\u7684\u76f8\u5bb9\u6027\uff0c\u907f\u514d\u51fa\u73b0\u5206\u5c42\u3001\u6790\u51fa\u7b49\u73b0\u8c61\u3002<\/li>\n<li><strong>\u7ec4\u5408\u4f7f\u7528\uff1a<\/strong> \u6839\u636e\u5e94\u7528\u9700\u6c42\uff0c\u53ef\u4ee5\u5c06\u591a\u79cd\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u7ec4\u5408\u4f7f\u7528\uff0c\u4ee5\u5b9e\u73b0\u66f4\u4f73\u7684\u9632\u62a4\u6548\u679c\u3002 \u4f8b\u5982\uff0c\u53ef\u4ee5\u5c06\u7d2b\u5916\u7ebf\u5438\u6536\u5242\u4e0e\u53d7\u963b\u80fa\u5149\u7a33\u5b9a\u5242\u3001\u6297\u6c27\u5242\u7b49\u7ec4\u5408\u4f7f\u7528\uff0c\u5f62\u6210\u534f\u540c\u6548\u5e94\u3002<\/li>\n<\/ul>\n<p><strong>\u4e03\u3001\u672a\u6765\u7684\u5c55\u671b\uff1a\u8ba9\u73af\u6c27\u6811\u8102\u201c\u6c38\u8446\u9752\u6625\u201d<\/strong><\/p>\n<p>\u968f\u7740\u79d1\u6280\u7684\u4e0d\u65ad\u53d1\u5c55\uff0c\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\u4e5f\u5728\u4e0d\u65ad\u521b\u65b0\u3002\u672a\u6765\u7684\u53d1\u5c55\u8d8b\u52bf\u53ef\u80fd\u5305\u62ec\uff1a<\/p>\n<ul>\n<li><strong>\u65b0\u578b\u9ad8\u6548\u7684\u8010\u9ec4\u53d8\u4fc3\u8fdb\u5242\uff1a<\/strong> 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